The aim of this study was to determine the brain structures as well as the plasticity events
associated with the behavioral effects of cholinergic damage. Rats were submitted to
injection of 192 IgG-saporin in the medial septum/diagonal band of Broca complex and the
nucleus basalis magnocellularis. The immunohistochemical expression of c-Fos protein and
PSA-NCAM (polysialylated neural cell adhesion molecule) and the behavioral performances
in the nonmatching-to-position task were assessed at various post-lesion times. Thus, 3 …